2016.06.17 CSCS Daily Study Question:
Upon microscopic inspection of a muscle cell, you see that the calcium concentration of the sarcoplasm is high and the calcium concentration of the sarcoplasmic reticulum is low. Given these observations, which of the following statements is most accurate?
(A) The A-band of the muscle cell sarcomere has shortened
(B) Acetylcholine is likely present in the adjacent neuromuscular junction
(C) Calcium is currently bound to tropomyosin
(D) Tension within the muscle cell is low
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Correct Answer:
(B) Acetylcholine is likely present in the adjacent neuromuscular junction
Explanation:
When calcium concentration in the sarcoplasm is high and the calcium concentration in the sarcoplasmic reticulum is low, you can assume that the muscle is in its active state, and therefore generating tension (choice D is wrong). The initial stages of muscle cell activation involve the arrival of the neurotransmitter acetylcholine. Acetylcholine is released into the neuromuscular junction from the motor neuron. As for the other incorrect answers, the A-band of the sarcomere corresponds with the length of myosin (thick) filaments and does not change in size (choice A is wrong). Also when muscle cells are activated, calcium binds to troponin, not tropomyosin (choice C is wrong).
Reference:
Essentials of Strength Training & Conditioning 3rd edition p. 5 – 9
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2016.06.17 CSCS Daily Study Question